![]() The present results show that coenzyme Q10 supplementation (50 mg twice daily) effectively reduced statin-related mild-to-moderate muscular symptoms, causing lower interference of statin-related muscular symptoms with daily activities. From baseline, no differences in liver and muscle enzymes or cholesterol values were found. Background: The aim of this study was to assess the long-term effects of smoking and to investigate the permanence of this damage to the oral microcirculation. The relative values of PSS and PIS significantly decreased (-33.1% and -40.3%, respectively) in the Q10 group compared to placebo group (both P<0.05). ![]() Coenzyme Q10 supplementation decreased statin-related muscle symptoms in 75% of patients. In the placebo group, PSS and PIS did not change. The Pain Interference Score (PIS) after Q10 supplementation was reduced from 4.0☐.4 to 2.6☐.4 (P<0.001). The intensity of muscle pain, measured as the Pain Severity Score (PSS), in the Q10 group was reduced from 3.9☐.4 to 2.9☐.4 (P<0.001). Medical Science Monitor is an international, peer-reviewed scientific journal that publishes original articles in basic, clinical, and related biomedical disciplines such as epidemiology, public health, and medical technology. The Brief Pain Inventory (BPI) questionnaire was used and blood testing was performed at inclusion in the study and after 30 days of supplementation. Editorial: Maternal SARS-CoV-2 Infection and Pregnancy Outcomes from Current Global Study Data. It is the standardised abbreviation to be used for abstracting, indexing and referencing. The Q10 group (n=25) received coenzyme Q10 supplementation over a period of 30 days (50 mg twice daily), and the control group (n=25) received placebo. The ISO4 abbreviation of Medical Science Monitor is Med. Herein, we tested whether coenzyme Q10 supplementation could decrease statin-associated muscular pain in a specific group of patients with mild-to-moderate muscle symptoms.įifty patients treated with statins and reporting muscle pain were recruited. Coenzyme Q10 supplementation has yielded conflicting results in decreasing statin myopathy. Statin use is frequently associated with muscle-related symptoms.
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